[Multisystem inflammatory syndrome associated with COVID-19: Not just a pediatric disease]

Ned Tijdschr Geneeskd. 2021 Jul 29:165:D5724.
[Article in Dutch]

Abstract

Background: Since the start of the COVID-19 pandemic, a hyperinflammatory syndrome has appeared which develops weeks after a SARS-CoV-2 infection. This multisystem inflammatory syndrome has been described mainly in children (MIS-C), but lately has also been found in adults (MIS-A).

Case description: We present a case of a woman with MIS-A. She had fever, diarrhoea, hypotension, laboratory abnormalities with high inflammatory markers, coagulation parameters, troponin-T, N-terminal pro-brain natriuretic peptide (NT-proBNP). Her electrocardiogram had marked diffuse ST-depressions. She was diagnosed in an early stage of MIS-A and treated successfully with immune suppression, antiaggregants and anticoagulants.

Conclusion: MIS-A and MIS-C are similar, potentially life-threatening inflammatory syndromes which can lead to severe cardiac dysfunction and cardiovascular failure. For effective treatment and prevention of complications, timely recognition is essential. Clinicians should therefore be mindful of this multisystem inflammatory syndrome, not just in children but also in adults.

Publication types

  • Case Reports

MeSH terms

  • COVID-19*
  • Female
  • Humans
  • Pandemics
  • SARS-CoV-2
  • Syndrome
  • Systemic Inflammatory Response Syndrome

Supplementary concepts

  • pediatric multisystem inflammatory disease, COVID-19 related