Understanding the fundamentals of microbial remediation with emphasize on metabolomics

Prep Biochem Biotechnol. 2022;52(3):351-363. doi: 10.1080/10826068.2021.1946694. Epub 2021 Aug 1.

Abstract

The post-genomic tool metabolomics is a great advancement in science and technology which acquires novel strategies and pathways to analyze various biological compounds. Metabolomics aids in retrieving the qualitative and quantitative data from the various biological system. The current review is focused on the application of metabolomics in bioremediation and helps to focus on the xenobiotic compounds which are discharged into the environment and have long term impact. The microbial based biodegradation can be effectively used along with the combination of metabolomic approach for a better understanding of the breakdown of certain recalcitrant. Additionally, this review also discusses the candidate gene approach which helps to comprehend the functional analysis of microbial genes in response to different contaminants. Therefore, this review intends to discuss the metabolomics in bioremediation by studying the complete set of metabolites involved during the process of degradation and their interaction with the environment.

Keywords: Biodegradation; Metabolites; Metabolomics; Recalcitrant; Toxicology; Xenobiotic compounds.

Publication types

  • Review

MeSH terms

  • Biodegradation, Environmental*
  • Environmental Pollutants / metabolism*
  • Metabolomics*
  • Xenobiotics / metabolism*

Substances

  • Environmental Pollutants
  • Xenobiotics