Ozone eliminates novel coronavirus Sars-CoV-2 in mucosal samples

F Sallustio; G Cardinale; S Voccola; A Picerno; P Porcaro; L Gesualdo

doi:10.1016/j.nmni.2021.100927

Ozone eliminates novel coronavirus Sars-CoV-2 in mucosal samples

New Microbes New Infect. 2021 Sep:43:100927. doi: 10.1016/j.nmni.2021.100927. Epub 2021 Jul 24.

Authors

F Sallustio¹, G Cardinale², S Voccola³, A Picerno⁴, P Porcaro², L Gesualdo²

Affiliations

¹ Department of Interdisciplinary Medicine, University of Bari "Aldo Moro", Bari, Italy.
² Consorzio Sannio Tech, Apollosa, Benevento, Italy.
³ Genus Biotech, Apollosa, Benevento, Italy.
⁴ Nephrology, Dialysis and Transplantation Unit, DETO, University of Bari "Aldo Moro", Bari, Italy.

Abstract

Recent investigations have shown that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is able to resist on the surfaces and that the diffusion occurs through droplets that can remain suspended in the air as an aerosol. The ozone generated in situ from oxygen is an active ingredient with a 'biocidal' action, but little is known about its capacity to inactivate specifically SARS-CoV-2. Here we show, for the first time, the efficiency of the ozone treatment to neutralize the SARS-CoV-2 present in nasopharynx secretion samples with high viral load. Our data show that ozone is effective in SARS-CoV-2 elimination.

Keywords: COVID-19; Sars-CoV-2; disinfection; ozone.