18F-FDG PET/CT Imaging Features of Cardiac Arrhythmia in a Patient Treated with Panitumumab

J Nucl Med Technol. 2021 Dec;49(4):360-361. doi: 10.2967/jnmt.121.262216. Epub 2021 Jul 30.

Abstract

Panitumumab is a new humanized antiepidermal growth factor receptor monoclonal antibody (mAb) approved for the treatment of advanced colorectal cancer. There is an increase in the use of this drug due to a good response rate and possible secondary resection in advanced colorectal cancer. Here, we present 18F-FDG PET/CT imaging findings of cardiac arrhythmia in a patient receiving panitumumab for the treatment of metastatic infiltrating rectal adenocarcinoma. Cardiotoxicity is a known adverse effect associated with panitumumab. So far, to our knowledge, no documented imaging findings for the same are available in the literature.

Keywords: PET; PET/CT; cardiac arrhythmia; panitumumab.

MeSH terms

  • Antibodies, Monoclonal / adverse effects
  • Arrhythmias, Cardiac
  • Fluorodeoxyglucose F18*
  • Humans
  • Panitumumab / adverse effects
  • Positron Emission Tomography Computed Tomography*

Substances

  • Antibodies, Monoclonal
  • Fluorodeoxyglucose F18
  • Panitumumab