Matrix-assisted laser desorption ionization - mass spectrometry imaging of erlotinib reveals a limited tumor tissue distribution in a non-small-cell lung cancer mouse xenograft model

Clin Transl Med. 2021 Jul;11(7):e481. doi: 10.1002/ctm2.481.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Carcinoma, Non-Small-Cell Lung / drug therapy
  • Carcinoma, Non-Small-Cell Lung / pathology
  • Cell Line, Tumor
  • Erlotinib Hydrochloride / metabolism*
  • Erlotinib Hydrochloride / therapeutic use
  • Humans
  • Kidney / chemistry
  • Kidney / diagnostic imaging
  • Kidney / metabolism*
  • Liver / chemistry
  • Liver / diagnostic imaging
  • Liver / metabolism*
  • Lung Neoplasms / drug therapy
  • Lung Neoplasms / pathology
  • Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization* / methods
  • Tissue Distribution
  • Transplantation, Heterologous

Substances

  • Erlotinib Hydrochloride