A new palatable oral rehydration solution: A randomised controlled cross-over study in patients with a high output stoma

J Hum Nutr Diet. 2022 Feb;35(1):94-101. doi: 10.1111/jhn.12935. Epub 2021 Sep 5.

Abstract

Background: Patients with a jejunostomy or high output stoma may need a glucose-sodium oral rehydration solution drink to maintain hydration. These solutions are unpalatable and a new flavoured pre-packaged solution was developed.

Methods: After 8 h of fasting, 27 patients took 500 mL of the modified World Health Organization (WHO) cholera solution or Glucodrate® (Vitaflo) on two occasions in a cross-over random order and urine and stomal output was collected for 6 h.

Results: There was a small but significant difference in net sodium absorption in favour of the modified WHO cholera solution (10 ± 28 mmol modified WHO cholera solution vs. -1 ± 26 mmol Glucodrate®, p = 0.01). However the Glucodrate® was more palatable, with 24 patients (89%) preferring it to the modified WHO cholera solution (p < 0.005).

Conclusions: Glucodrate® is a more palatable solution than the modified WHO cholera solution and is almost as effective and so can be used when patients find the modified WHO cholera solution unpalatable.

Keywords: high output stoma; ileostomy; jejunostomy; oral rehydration solution; palatability.

Publication types

  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cholera* / therapy
  • Cross-Over Studies
  • Diarrhea
  • Fluid Therapy
  • Glucose
  • Humans
  • Rehydration Solutions*
  • Sodium

Substances

  • Rehydration Solutions
  • Sodium
  • Glucose