Surgical navigation for challenging recurrent or pretreated intra-abdominal and pelvic soft tissue sarcomas

J Surg Oncol. 2021 Dec;124(7):1173-1181. doi: 10.1002/jso.26624. Epub 2021 Jul 28.

Abstract

Background: This study assessed whether electromagnetic navigation can be of added value during resection of recurrent or post-therapy intra-abdominal/pelvic soft tissue sarcomas (STS) in challenging locations.

Materials and methods: Patients were included in a prospective navigation study. A pre-operatively 3D roadmap was made and tracked using electromagnetic reference markers. During the operation, an electromagnetic pointer was used for the localization of the tumor/critical anatomical structures. The primary endpoint was feasibility, secondary outcomes were safety and usability.

Results: Nine patients with a total of 12 tumors were included, 7 patients with locally recurrent sarcoma. Three patients received neoadjuvant radiotherapy and three other patients received neoadjuvant systemic treatment. The median tumor size was 4.6 cm (2.4-10.4). The majority of distances from tumor to critical anatomical structures was <0.5 cm. The tumors were localized using the navigation system without technical or safety issues. Despite the challenging nature of these resections, 89% were R0 resections, with a median blood loss of 100 ml (20-1050) and one incident of vascular damage. Based on the survey, surgeons stated navigation resulted in shorter surgery time and made the resections easier.

Conclusion: Electromagnetic navigation facilitates resections of challenging lower intra-abdominal/pelvic STS and might be of added value.

Keywords: electromagnetic tracking; intra-abdominal sarcoma; pelvic sarcoma; soft tissue sarcoma; surgical navigation.

MeSH terms

  • Abdominal Neoplasms / diagnostic imaging
  • Abdominal Neoplasms / surgery*
  • Aged
  • Blood Loss, Surgical
  • Contrast Media
  • Female
  • Humans
  • Imaging, Three-Dimensional
  • Male
  • Middle Aged
  • Neoplasm Recurrence, Local / diagnostic imaging
  • Neoplasm Recurrence, Local / surgery*
  • Operative Time
  • Pelvic Neoplasms / diagnostic imaging
  • Pelvic Neoplasms / surgery*
  • Prospective Studies
  • Sarcoma / diagnostic imaging
  • Sarcoma / surgery*
  • Soft Tissue Neoplasms / diagnostic imaging
  • Soft Tissue Neoplasms / surgery*
  • Surgery, Computer-Assisted*
  • Tomography, X-Ray Computed

Substances

  • Contrast Media