Perioperative Management of Takayasu Arteritis for Cardiac Surgery in a Patient Treated With Tocilizumab

Yoh Arita; Yoshikazu Nakaoka; Yuko Eda; Katsukiyo Kitabayashi; Shinji Hasegawa

doi:10.1016/j.jaccas.2020.07.039

Perioperative Management of Takayasu Arteritis for Cardiac Surgery in a Patient Treated With Tocilizumab

JACC Case Rep. 2020 Oct 7;2(15):2363-2367. doi: 10.1016/j.jaccas.2020.07.039. eCollection 2020 Dec.

Authors

Yoh Arita¹, Yoshikazu Nakaoka^{2

3}, Yuko Eda¹, Katsukiyo Kitabayashi⁴, Shinji Hasegawa¹

Affiliations

¹ Department of Cardiology, Japan Community Healthcare Organization Osaka Hospital, Osaka, Japan.
² Department of Vascular Physiology, National Cerebral and Cardiovascular Center Research Institute, Suita, Japan.
³ Department of Cardiovascular Medicine, Osaka University Graduate School of Medicine, Osaka, Japan.
⁴ Cardiovascular Surgery, Japan Community Healthcare Organization Osaka Hospital, Osaka, Japan.

Abstract

We describe the case of a young woman with Takayasu arteritis with severe stenosis in the main trunk of the left coronary artery. After administration of prednisolone and tocilizumab to control disease activity, coronary artery bypass grafting was performed. Here, we report the successful perioperative management of this cardiac surgery. (Level of Difficulty: Advanced.).

Keywords: CABG, coronary artery bypass graft; CRP, C-reactive protein; CT, computed tomography; ESR, erythrocyte sedimentation rate; GC, glucocorticoid; IL, interleukin; LMCA, left main coronary artery; PSL, prednisolone; SAA, serum amyloid A; TAK, Takayasu arteritis; TCZ, tocilizumab; Takayasu arteritis; disease activity; interleukin-6; perioperative management; tocilizumab.

Publication types

Case Reports