ZrO2/CeO2/polyacrylic acid nanocomposites with alkaline phosphatase-like activity for sensing

Xiangchuan Wu; Jinhui Wei; Chengyuan Wu; Guangping Lv; Lina Wu

doi:10.1016/j.saa.2021.120165

ZrO₂/CeO₂/polyacrylic acid nanocomposites with alkaline phosphatase-like activity for sensing

Spectrochim Acta A Mol Biomol Spectrosc. 2021 Dec 15:263:120165. doi: 10.1016/j.saa.2021.120165. Epub 2021 Jul 10.

Authors

Xiangchuan Wu¹, Jinhui Wei¹, Chengyuan Wu¹, Guangping Lv¹, Lina Wu²

Affiliations

¹ School of Food Science and Pharmaceutical Engineering, Nanjing Normal University, Nanjing 210023, PR China.
² School of Food Science and Pharmaceutical Engineering, Nanjing Normal University, Nanjing 210023, PR China. Electronic address: wuln@njnu.edu.cn.

PMID: 34304012
DOI: 10.1016/j.saa.2021.120165

Abstract

In the present work, we synthesized ZrO₂/CeO₂/polyacrylic acid (PAA) nanocomposites (nanozyme) with phosphatase-like activity. ZrO₂ evenly distributed in CeO₂ nanorods considered as lewis acids to enhance the phosphatase-like activity of CeO₂ nanorods. Furthermore, PAA was used to coat ZrO₂/CeO₂/ nanorods and improve the dispersion, stability and robustness. The ZrO₂/CeO₂/PAA nanocomposites had 100% enhanced phosphatase-like activity compared with CeO₂ nanorods and excellent adaptability in a wide pH range from 4.0 to 12.0. ZrO₂/CeO₂/PAA nanocomposites could hydrolyze methyl parathion (MP) to p-nitrophenol (p-NP) with bright yellow color for colorimetric detection. The developed colorimetric detection system showed a linear response from 7.60 × 10^-11-7.60 × 10^-8 M with a detection limit of 0.021 nM and was successfully applied for the determination of MP in corn samples.

Keywords: Detection; Methyl parathion; Phosphatase-like activity; ZrO(2)/CeO(2)/PAA nanocomposites.

MeSH terms

Acrylic Resins
Alkaline Phosphatase
Cerium*
Nanocomposites*

Substances

Acrylic Resins
Cerium
carbopol 940
Alkaline Phosphatase