The Role of Dietary Nutrients in Peripheral Nerve Regeneration

Int J Mol Sci. 2021 Jul 10;22(14):7417. doi: 10.3390/ijms22147417.

Abstract

Peripheral nerves are highly susceptible to injuries induced from everyday activities such as falling or work and sport accidents as well as more severe incidents such as car and motorcycle accidents. Many efforts have been made to improve nerve regeneration, but a satisfactory outcome is still unachieved, highlighting the need for easy to apply supportive strategies for stimulating nerve growth and functional recovery. Recent focus has been made on the effect of the consumed diet and its relation to healthy and well-functioning body systems. Normally, a balanced, healthy daily diet should provide our body with all the needed nutritional elements for maintaining correct function. The health of the central and peripheral nervous system is largely dependent on balanced nutrients supply. While already addressed in many reviews with different focus, we comprehensively review here the possible role of different nutrients in maintaining a healthy peripheral nervous system and their possible role in supporting the process of peripheral nerve regeneration. In fact, many dietary supplements have already demonstrated an important role in peripheral nerve development and regeneration; thus, a tailored dietary plan supplied to a patient following nerve injury could play a non-negotiable role in accelerating and promoting the process of nerve regeneration.

Keywords: dietary regimens; macronutrients; micronutrients; minerals; nerve injury; peripheral nervous system; vitamins.

Publication types

  • Review

MeSH terms

  • Animals
  • Diet*
  • Humans
  • Nerve Regeneration*
  • Nutrients / pharmacology*
  • Peripheral Nerve Injuries / therapy*
  • Peripheral Nerves / cytology*
  • Peripheral Nerves / drug effects
  • Recovery of Function