Time Course of Neutralizing Antibody in Health Care Workers With Mild or Asymptomatic COVID-19 Infection

Ilaria Vicenti; Francesca Gatti; Renzo Scaggiante; Adele Boccuto; Eliana Modolo; Daniela Zago; Monica Basso; Filippo Dragoni; Niccolo' Bartolini; Maurizio Zazzi; Saverio Giuseppe Parisi

doi:10.1093/ofid/ofab312

Time Course of Neutralizing Antibody in Health Care Workers With Mild or Asymptomatic COVID-19 Infection

Open Forum Infect Dis. 2021 Jun 12;8(7):ofab312. doi: 10.1093/ofid/ofab312. eCollection 2021 Jul.

Affiliations

¹ Department of Medical Biotechnologies, University of Siena, Siena, Italy.
² Department of Molecular Medicine University of Padova, Padova, Italy.
³ Belluno Hospital, Belluno, Italy.

Abstract

We describe the time course of neutralizing antibody (NtAb) titer in a cohort of health care workers with mild or asymptomatic severe acute respiratory syndrome coronavirus (SARS-CoV-2) infection. NtAb levels decreased over time; however, serum neutralizing activity remained detectable after a median of 7 months from SARS-CoV-2 diagnosis in the majority of cases.

Keywords: SARS-CoV-2; follow-up; health care workers; mild or asymptomatic infection; neutralizing antibody titer.