Corneal biomechanical properties in patients with kidney transplant

Vaibhav Kumar Jain; Rachna Agarwal; Shabari Pal; Jaya Kaushik; Kumudini Sharma; Vikas Kanaujia

doi:10.4103/tjo.tjo_24_20

Corneal biomechanical properties in patients with kidney transplant

Taiwan J Ophthalmol. 2020 Oct 7;11(2):141-145. doi: 10.4103/tjo.tjo_24_20. eCollection 2021 Apr-Jun.

Authors

Vaibhav Kumar Jain¹, Rachna Agarwal¹, Shabari Pal¹, Jaya Kaushik², Kumudini Sharma¹, Vikas Kanaujia¹

Affiliations

¹ Department of Ophthalmology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.
² Department of Ophthalmology, Armed Forces Medical College, Pune, Maharashtra, India.

Abstract

Purpose: The purpose of the study was to evaluate the corneal biomechanical properties in patients post kidney transplant and to compare them with healthy age-matched control.

Materials and methods: In this cross-sectional study, 68 patients with kidney transplant (study group) and 68 healthy individuals (control group) were analyzed with ocular response analyzer measurements. Only the right eye of each participant was assessed for corneal hysteresis (CH), corneal resistance factor (CRF), corneal-compensated intraocular pressure (IOP_cc), and Goldmann-correlated intraocular pressure (IOP_g).

Results: The mean CH in the study group was 9.70 ± 1.62 mmHg which was significantly lower than the control group with the mean CH of 10.60 ± 1.49 mmHg (P = 0.001). The mean IOP_cc was 18.17 ± 4.00 mmHg and 16.00 ± 3.94 mmHg in the study and control groups, respectively (P = 0.002). CRF and IOP_g were not significantly different between groups.

Conclusion: CH and IOP_ccare altered in kidney transplant patients.

Keywords: Corneal biomechanical; corneal hysteresis; corneal resistance factor; intraocular pressure; kidney transplant; ocular response analyzer.