Effects of preparation parameters on the properties of the crosslinked pectin nanofiber mats

Jia Zheng; Qianwen Yang; Xiaoqi Shi; Zhigang Xie; Junli Hu; Yichun Liu

doi:10.1016/j.carbpol.2021.118314

Effects of preparation parameters on the properties of the crosslinked pectin nanofiber mats

Carbohydr Polym. 2021 Oct 1:269:118314. doi: 10.1016/j.carbpol.2021.118314. Epub 2021 Jun 8.

Authors

Jia Zheng¹, Qianwen Yang², Xiaoqi Shi³, Zhigang Xie⁴, Junli Hu⁵, Yichun Liu⁶

Affiliations

¹ Key Laboratory of UV-Emitting Materials and Technology (Northeast Normal University), Ministry of Education, Changchun, Jilin 130024, China. Electronic address: zhengj802@nenu.edu.cn.
² Key Laboratory of UV-Emitting Materials and Technology (Northeast Normal University), Ministry of Education, Changchun, Jilin 130024, China. Electronic address: yangqw247@nenu.edu.cn.
³ Key Laboratory of UV-Emitting Materials and Technology (Northeast Normal University), Ministry of Education, Changchun, Jilin 130024, China.
⁴ State Key Laboratory of Polymer Physics and Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin 130022, China. Electronic address: xiez@ciac.ac.cn.
⁵ Key Laboratory of UV-Emitting Materials and Technology (Northeast Normal University), Ministry of Education, Changchun, Jilin 130024, China. Electronic address: hujl100@nenu.edu.cn.
⁶ Key Laboratory of UV-Emitting Materials and Technology (Northeast Normal University), Ministry of Education, Changchun, Jilin 130024, China. Electronic address: ycliu@nenu.edu.cn.

PMID: 34294328
DOI: 10.1016/j.carbpol.2021.118314

Abstract

Pectin nanofiber mats prepared with periodate oxidation-electrospinning-adipic acid dihydrazide crosslinking strategy are promising for biomedical applications. In this study, we systematically examined the effects of electrospinning and crosslinking conditions on the properties of pectin nanofiber mats. The properties of mats were tunable in the range of 200-400 nm fiber size, 11-21% ADH residue content, 13-28 times absorbency, 13°-21° contact angle, 2 weeks or longer degradation time, 1.5-2.2 MPa tensile strength, 40-70% elongation, and 0.25-0.27 g/(cm²·24 h) permeability. Increasing polymer concentration, adipic acid dihydrazide amount, time or temperature could increase fiber size and its tensile strength, and decrease the absorbency, hydrophilicity, degradation rate, and elongation. These results indicate that controlling the process parameters can effectively regulate the properties of pectin nanofiber mats and meet the requirements of various biomedical applications.

Keywords: Crosslinking; Electrospinning; Polysaccharide; Property regulation.