When the cerebellum holds the starting gun

Jimena L Frontera; Clément Léna

doi:10.1016/j.neuron.2021.06.027

When the cerebellum holds the starting gun

Neuron. 2021 Jul 21;109(14):2207-2209. doi: 10.1016/j.neuron.2021.06.027.

Authors

Jimena L Frontera¹, Clément Léna²

Affiliations

¹ Neurophysiology of Brain Circuits Team, Institut de Biologie de l'Ecole normale supérieure (IBENS), Ecole normale supérieure, CNRS, INSERM, PSL Research University, 75005 Paris, France.
² Neurophysiology of Brain Circuits Team, Institut de Biologie de l'Ecole normale supérieure (IBENS), Ecole normale supérieure, CNRS, INSERM, PSL Research University, 75005 Paris, France. Electronic address: lena@biologie.ens.fr.

PMID: 34293289
DOI: 10.1016/j.neuron.2021.06.027

Abstract

How the cerebellum affects movement onset is poorly understood. In this issue of Neuron, Dacre et al. (2021) establish that in the context of operant conditioning, the transient activation of the cerebello-thalamo-cortical pathway to the motor cortex is sufficient to initiate the conditioned movement.

Keywords: 2-photon imaging; Awake intracellular recordings; Motor cortex; Movement initiation; Operant conditioning.

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MeSH terms

Cerebellum*
Motor Cortex*
Movement
Neurons