Nutritional Impact and Its Potential Consequences on COVID-19 Severity

Esmaeil Mortaz; Gillina Bezemer; Shamila D Alipoor; Mohammad Varahram; Sharon Mumby; Gert Folkerts; Johan Garssen; Ian M Adcock

doi:10.3389/fnut.2021.698617

Nutritional Impact and Its Potential Consequences on COVID-19 Severity

Front Nutr. 2021 Jul 5:8:698617. doi: 10.3389/fnut.2021.698617. eCollection 2021.

Authors

Esmaeil Mortaz^{1

2}, Gillina Bezemer^{3

4}, Shamila D Alipoor⁵, Mohammad Varahram⁶, Sharon Mumby⁷, Gert Folkerts³, Johan Garssen^{3

8}, Ian M Adcock⁷

Affiliations

¹ Department of Immunology, Faculty of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
² Clinical Tuberculosis and Epidemiology Research Centre, National Research Institute of Tuberculosis and Lung Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
³ Division of Pharmacology, Faculty of Science, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, Netherlands.
⁴ Impact Station, Hilversum, Netherlands.
⁵ Molecular Medicine Department, Institute of Medical Biotechnology, National Institute of Genetic Engineering and Biotechnology, Tehran, Iran.
⁶ Mycobacteriology Research Centre, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran.
⁷ Airways Disease Section, Faculty of Medicine, National Heart and Lung Institute, Imperial College London, London, United Kingdom.
⁸ Center of Excellence Immunology, Nutricia Research, Utrecht, Netherlands.

Abstract

Background: During late 2019 a viral disease due to a novel coronavirus was reported in Wuhan, China, which rapidly developed into an exploding pandemic and poses a severe threat to human health all over the world. Until now (May 2021), there are insufficient treatment options for the management of this global disease and shortage of vaccines. Important aspects that help to defeat coronavirus infection seems to be having a healthy, strong, and resilient immune system. Nutrition and metabolic disorders, such as obesity and diabetes play a crucial role on the community health situation in general and especially during this new pandemic. There seems to be an enormous impact of lifestyle, metabolic disorders, and immune status on coronavirus disease 2019 (COVID-19) severity and recovery. For this reason, it is important to consider the impact of lifestyle and the consumption of well-defined healthy diets during the pandemic. Aims: In this review, we summarise recent findings on the effect of nutrition on COVID-19 susceptibility and disease severity and treatment. Understanding how specific dietary features might help to improve the public health strategies to reduce the rate and severity of COVID-19.

Keywords: COVID-19; SARS-CoV-2; nutrition; probiotics; proteins.

Publication types

Review

Abstract

Publication types

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