ASPEN definitions in pediatric intestinal failure

Biren P Modi; David P Galloway; Kathleen Gura; Anita Nucci; Steven Plogsted; Alyssa Tucker; Paul W Wales

doi:10.1002/jpen.2232

ASPEN definitions in pediatric intestinal failure

JPEN J Parenter Enteral Nutr. 2022 Jan;46(1):42-59. doi: 10.1002/jpen.2232. Epub 2021 Sep 15.

Authors

Biren P Modi¹, David P Galloway², Kathleen Gura³, Anita Nucci⁴, Steven Plogsted⁵, Alyssa Tucker⁶, Paul W Wales⁷

Affiliations

¹ Center for Advanced Intestinal Rehabilitation, Department of Surgery, Boston Children's Hospital and Harvard Medical School, Boston, Massachusetts, USA.
² Division of Gastroenterology, Hepatology and Nutrition, University of Alabama at Birmingham, Birmingham, Alabama, USA.
³ Division of Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital and Harvard Medical School, Boston, Massachusetts, USA.
⁴ Department of Nutrition, Georgia State University, Atlanta, Georgia, USA.
⁵ Columbus, Ohio, USA.
⁶ Department of Clinical Nutrition, Children's National Medical Center, Washington, DC, USA.
⁷ Group for Improvement of Intestinal Function and Treatment, Department of Surgery, Hospital for Sick Children and University of Toronto, Toronto, Ontario, Canada.

PMID: 34287974
DOI: 10.1002/jpen.2232

Abstract

Pediatric intestinal failure (PIF) is a relatively rare disease entity that requires focused interdisciplinary care and specialized nutrition management. There has long been a lack of consensus in the definition of key terms related to PIF because of its rarity and a plethora of small studies rather than large trials. As such, the American Society for Parenteral and Enteral Nutrition (ASPEN) PIF Section, composed of clinicians from a variety of disciplines caring for children with intestinal failure, is uniquely poised to provide insight into this definition void. This document is the product of an effort by the Section to create evidence-based consensus definitions, with the goal of allowing for appropriate comparisons between clinical studies and measurement of long-term patient outcomes. This paper has been approved by the ASPEN Board of Directors.

Keywords: definition; enteral nutrition; intestinal failure; parenteral nutrition; pediatrics; short bowel syndrome.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Child
Consensus
Enteral Nutrition
Humans
Intestinal Failure*
Parenteral Nutrition
Short Bowel Syndrome* / therapy