A typical clinical symptom of human norovirus infection is projectile vomiting. Although norovirus RNA and viral particles have been detected in vomitus, infectivity has not yet been reported. We detected replication-competent norovirus in 25% of vomit samples with a 13-fold to 714-fold increase in genomic equivalents, confirming infectious norovirus.
Keywords: Norwalk virus; Sweden; enteric infections; human intestinal enteroids; infectivity; norovirus; viruses; vomit.