Chlorhexidine Mouthwash Fails to Eradicate Oropharyngeal Gonorrhea in a Clinical Pilot Trial (MoNg)

Sex Transm Dis. 2022 Feb 1;49(2):e38-e41. doi: 10.1097/OLQ.0000000000001515.

Abstract

This single-arm open-label pilot trial in Antwerp, Belgium, was ended early in accordance with the protocol because twice-daily gargling with chlorhexidine 0.2% for 6 days failed to eradicate Neisseria gonorrhoeae from the oropharynx of asymptomatic men who have sex with men (n = 3; efficacy of 0%; 95% confidence interval, 0%-56.1%).

Publication types

  • Clinical Trial

MeSH terms

  • Chlorhexidine
  • Gonorrhea* / drug therapy
  • Gonorrhea* / prevention & control
  • Homosexuality, Male
  • Humans
  • Male
  • Mouthwashes
  • Neisseria gonorrhoeae
  • Oropharynx
  • Pilot Projects
  • Sexual and Gender Minorities*

Substances

  • Mouthwashes
  • Chlorhexidine