The best sugar in town for malaria transmission

Trends Parasitol. 2021 Sep;37(9):775-776. doi: 10.1016/j.pt.2021.07.001. Epub 2021 Jul 15.

Abstract

Anopheles mosquitoes feed on plant nectars as their main source of sugar. Wang et al. show that Asaia bacteria proliferate in the midgut of mosquitoes that feed on glucose or trehalose. Asaia increases the lumenal pH by downregulating mosquito vacuolar ATPase expression, therefore increasing Plasmodium gametogenesis and vector competence.

Keywords: Anopheles; Plasmodium; glucose; microbiome; vectorial capacity.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, N.I.H., Intramural
  • Comment

MeSH terms

  • Animals
  • Anopheles*
  • Malaria*
  • Mosquito Vectors
  • Plasmodium*
  • Sugars

Substances

  • Sugars