Solar-Powered Whole-Cell P450 Catalytic Platform for C-Hydroxylation Reactions

ChemSusChem. 2021 Aug 9;14(15):3030. doi: 10.1002/cssc.202101373. Epub 2021 Jul 16.

Abstract

Invited for this month's cover is the joint research group of Prof. Chan Beum Park at the Korea Advanced Institute of Science and Technology (KAIST) and Prof. Chul-Ho Yun at the Chonnam National University (CNU). The image shows how the use of a natural photosensitizer, flavin mononucleotide, and visible light can lead to a cost-effective, green, and sustainable process for P450-catalyzed reactions in a whole-cell system. The Communication itself is available at 10.1002/cssc.202100944.

MeSH terms

  • Catalysis
  • Chlorzoxazone / chemistry
  • Cytochrome P-450 Enzyme System / chemistry*
  • Escherichia coli / metabolism
  • Flavin Mononucleotide / chemistry*
  • Hydroxylation
  • Light
  • Nitrophenols / chemistry
  • Oxidation-Reduction
  • Photosensitizing Agents / chemistry*
  • Photosynthesis
  • Solar Energy

Substances

  • Nitrophenols
  • Photosensitizing Agents
  • Flavin Mononucleotide
  • Cytochrome P-450 Enzyme System
  • Chlorzoxazone
  • 4-nitrophenol