Customised, individually made total knee arthroplasty shows promising 1-year clinical and patient reported outcomes

Céline S Moret; Michael T Hirschmann; Nicole Vogel; Markus P Arnold

doi:10.1007/s00402-021-04045-1

Customised, individually made total knee arthroplasty shows promising 1-year clinical and patient reported outcomes

Arch Orthop Trauma Surg. 2021 Dec;141(12):2217-2225. doi: 10.1007/s00402-021-04045-1. Epub 2021 Jul 16.

Authors

Céline S Moret^#¹, Michael T Hirschmann^#², Nicole Vogel³, Markus P Arnold³

Affiliations

¹ Department of Orthopaedic Surgery and Traumatology, University of Basel, Kantonsspital Baselland, 4101, Bruderholz, Switzerland.
² Department of Orthopaedic Surgery and Traumatology, University of Basel, Kantonsspital Baselland, 4101, Bruderholz, Switzerland. michael.hirschmann@unibas.ch.
³ Practice Leonardo, Hirslanden Klinik Birshof, Reinacherstrasse 28, 4142, Münchenstein, Switzerland.

^# Contributed equally.

Abstract

Introduction: Customised individually made (CIM) implants for total knee arthroplasty (TKA) were introduced about 10 years ago. These implants aim to reduce the risk of prosthesis-related issues resulting from anthropometric differences between different knees. The purpose of this study was to analyse the short-term clinical outcome and patient reported outcome measures (PROMs) of a specific CIM implant, the ORIGIN^® knee replacement system (Symbios, Yverdon-les-Bains, Switzerland), which was introduced in 2018.

Materials and methods: This is a prospective cohort study of patients undergoing primary posterior-stabilised (PS) CIM TKA using the specific ORIGIN^® knee replacement system, (Symbios, Yverdon-les-Bains, Switzerland). TKAs were performed from February 2019 to October 2020. Data was collected preoperatively and postoperatively at 4 and 12 months. Outcome measures included the objective part of the Knee Society Score (KSS) with the range of motion (ROM) and the following PROMs: the Knee injury and Osteoarthritis Outcome Score (KOOS), the Forgotten Joint Score (FJS-12), the EuroQol, five dimensions, three levels (EQ-5D-3L) with the EuroQol visual analogue scale (EQ-VAS) and patient satisfaction. Differences in pre- to preoperative data were assessed with paired sample t tests. A p value < 0.05 was considered significant.

Results: Twenty-five CIM TKA (20 patients, 8 female) were included. The mean age at surgery was 66 years (SD, 6.9). At 4 and 12 months, significant improvements in the KSS (p < 0.001), the ROM (p < 0.001), all KOOS subscales (p < 0.001), the FJS (p < 0.001) and the EQ-5D-3L (p < 0.026) were found. Satisfaction rate was 91% and 88% at 4 and 12 months, respectively. Intraoperative complications did not occur and no revision surgeries were undertaken.

Conclusions: The present study demonstrated significant improvements in the KSS and specific PROMs 1 year after CIM TKA. This study suggests that CIM TKA is a safe and suitable option, which can yield good clinical outcome and PROMs at least during short-term follow-up.

Keywords: Customised individually made; Knee Society Score; Patient reported outcome measures; Satisfaction; Total knee arthroplasty; patient-specific implants.

Publication types

Review

MeSH terms

Arthroplasty, Replacement, Knee*
Female
Humans
Knee Joint / surgery
Knee Prosthesis*
Osteoarthritis, Knee* / surgery
Patient Reported Outcome Measures
Prospective Studies
Range of Motion, Articular
Treatment Outcome