A case of lipoma, calcification, and brain malformations in the midline of the skull

Hideto Kanazawa; Kenji Gonda; Takamitsu Tamura; Seiichi Takenoshita

doi:10.1016/j.radcr.2021.05.073

A case of lipoma, calcification, and brain malformations in the midline of the skull

Radiol Case Rep. 2021 Jul 3;16(9):2509-2513. doi: 10.1016/j.radcr.2021.05.073. eCollection 2021 Sep.

Authors

Hideto Kanazawa^{1

2}, Kenji Gonda^{2

3

4}, Takamitsu Tamura^{1

2}, Seiichi Takenoshita⁴

Affiliations

¹ Department of Neurology, Daido Central Hospital, 1-1-37 Asato, Naha, Okinawa 902-0067, Japan.
² Daido Obesity and Metabolism Research Center, Naha, Okinawa, Japan.
³ Department of Gastrointestinal Tract Surgery, Fukushima Medical University, Fukushima, Japan.
⁴ President of Fukushima Medical University, Fukushima, Japan.

Abstract

Few cases of pericallosal lipoma with several other lesions, including specific forms of calcification and brain malformations, have been reported. We present the case of an asymptomatic 83-year-old man with a pericallosallipoma with peculiar symmetrical morphology in the midline of the skull. We posit that the lesions began forming in the very early embryonic period and were closely associated with the cranial neural crest cells. We report the neuroradiological findings of this characteristic lesion and discuss several literature reviews on the process of its formation.

Keywords: Cranial neural crest cells; Malformation; Pericallosal lipoma; Symmetry.

Publication types

Case Reports