Discovery of the novel HLA-B*52:49N allele in a Chinese individual

HLA. 2021 Dec;98(6):553-555. doi: 10.1111/tan.14368. Epub 2021 Jul 21.

Authors

Xu Zhang^{1

2}, Feng-Qiu Lin^{1

2}, Xiao-Feng Li^{1

2}, Jian-Ping Li^{1

2

3

4

5}

Affiliations

¹ HLA Laboratory, Liaoning Blood Center, Shenyang, Liaoning, China.
² Key Laboratory of Blood Safety Research of Liaoning, Shenyang, Liaoning, China.
³ Department of Pharmacology, School of Pharmacy, China Medical University, Shenyang, Liaoning, China.
⁴ HLA Laboratory, Harbin Blood Center, Harbin, Heilongjiang, China.
⁵ Scientific Research Center of Shenyang Municipal Health Commission, Shenyang, Liaoning, China.

PMID: 34255438
DOI: 10.1111/tan.14368

Abstract

HLA-B*52:49N has one nucleotide change from HLA-B*52:01:01:01 where 601G (GAG) is changed to T(TAG).

Keywords: HLA-B*52:49N; sequencing; the novel allele.

© 2021 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Alleles
Base Sequence
China
Genes, MHC Class I*
HLA-B Antigens* / genetics
Humans
Sequence Analysis, DNA

Substances

HLA-B Antigens