Dietary Polyunsaturated Fatty Acids (PUFAs): Uses and Potential Health Benefits

Curr Nutr Rep. 2021 Sep;10(3):232-242. doi: 10.1007/s13668-021-00363-3. Epub 2021 Jul 13.

Abstract

Purpose of review: Polyunsaturated fatty acids (PUFAs) are obtained from various sources, which can be incorporated in the routine diet to maintain the health. They provide protection from several diseases like osteoarthritis, cancer, and autoimmune disorders. Major focus is given to the PUFAs omega-3 (ω-3) and omega-6 (ω-6) fatty acids which are available in both terrestrial and in the marine environment. The main concern of this article is to review the key scientific reports in context with the human health consequences and advantages of the food sources of ω-3 and ω-6 fatty acids.

Recent findings: ω-3 and ω-6 fatty acids are consumed by the population globally in the form of foods that are rich in fatty acids. Their nutritional effects have the capability to improve the physical functioning and metabolic rate of the body. These PUFAs contribute in various cellular activities like cell signaling, structural integrity and fluidity of cell membrane, the regulation of blood pressure, glucose level, the nervous system, inflammatory reactions, and hematic clotting. Animal and cell-based models represent that ω-3 and ω-6 PUFAs can regulate the skeletal muscle metabolism. The main concern of this article is to review the key scientific reports in context with the human health consequences and advantages of the food sources of ω-3 and ω-6 fatty acids.

Keywords: Food sources; Health benefits; Omega-3 fatty acid; Omega-6 fatty acid.

Publication types

  • Review

MeSH terms

  • Animals
  • Diet
  • Fatty Acids
  • Fatty Acids, Omega-3*
  • Fatty Acids, Omega-6*
  • Fatty Acids, Unsaturated
  • Humans

Substances

  • Fatty Acids
  • Fatty Acids, Omega-3
  • Fatty Acids, Omega-6
  • Fatty Acids, Unsaturated