100 years of physiology, discrimination and wonder

Diabet Med. 2021 Dec;38(12):e14642. doi: 10.1111/dme.14642. Epub 2021 Aug 17.

Abstract

There has been 100 years of research detailing the role of insulin in glucose, protein and free fatty acid metabolism. We explore the learnings though evolution and changes in management with an understanding of how it has impacted the care of people with diabetes. The discrimination endured is described and recent advances to empower and counter this are highlighted.

Keywords: evolution; insulin; type 1 diabetes.

Publication types

  • Historical Article
  • Review

MeSH terms

  • Animals
  • Biomedical Research / history*
  • Blood Glucose / metabolism*
  • Diabetes Mellitus, Experimental / history*
  • Diabetes Mellitus, Type 2 / blood
  • Diabetes Mellitus, Type 2 / drug therapy
  • Diabetes Mellitus, Type 2 / history*
  • History, 20th Century
  • Humans
  • Hypoglycemic Agents / history
  • Hypoglycemic Agents / pharmacology
  • Insulin / history*
  • Insulin / pharmacokinetics
  • Internal Medicine / history*
  • Lipid Metabolism*

Substances

  • Blood Glucose
  • Hypoglycemic Agents
  • Insulin