Testosterone replacement therapy in men with type 2 diabetes mellitus and functional hypogonadism -an Integrated Diabetes and Endocrine Academy (IDEA) consensus guideline

Abstract

Background: Though testosterone replacement therapy in men with organic hypogonadism is established, its role in men with type 2 diabetes mellitus (T2DM) and functional hypogonadism is unclear.

Methods: Thirteen experts addressed ten topic-specific questions after an in-depth review of literature, where all relevant issues were critically evaluated.

Results: Ten recommendations concerning diagnosis and management of men with T2DM and functional hypogonadism have been put forward.

Conclusion: Routine measurement of serum testosterone in all, and inappropriate replacement of testosterone in asymptomatic T2DM men with functional hypogonadism and borderline low serum testosterone values, is not recommended.

Keywords: Erectile dysfunction; Functional hypogonadism; Hypogonadism; Libido; Sexual dysfunction; Testosterone; Type 2 diabetes mellitus.