Neobladder and ablative pelvic radiotherapy: still a taboo?

Tumori. 2021 Dec;107(6):NP108-NP113. doi: 10.1177/03008916211031295. Epub 2021 Jul 8.

Abstract

The presence of a neobladder constitutes a limitation for the radiation oncologist, as there is no clear evidence about its tolerance to radiotherapy (RT). The limited literature only concerns the conventional postoperative treatment in patients with bladder cancer after cystectomy. Here we report a case of a patient with neobladder who underwent a stereotactic RT for a pelvic recurrence of disease, with response to treatment and no toxicity to the neobladder. This case represents a promising example of the chance to perform RT with ablative intent, using advanced techniques, even on lesions close to the neobladder.

Keywords: Neobladder; ablative radiotherapy; pelvic adenocarcinoma.

Publication types

  • Case Reports

MeSH terms

  • Clinical Decision-Making
  • Cystectomy / adverse effects
  • Cystectomy / methods
  • Disease Management
  • Humans
  • Male
  • Middle Aged
  • Neoplasm Metastasis
  • Neoplasm Staging
  • Organ Sparing Treatments
  • Organs at Risk
  • Pelvis / radiation effects
  • Postoperative Care*
  • Radiofrequency Therapy* / adverse effects
  • Radiofrequency Therapy* / methods
  • Tomography, X-Ray Computed
  • Treatment Outcome
  • Urinary Bladder Neoplasms / complications
  • Urinary Bladder Neoplasms / diagnosis
  • Urinary Bladder Neoplasms / radiotherapy*
  • Urinary Bladder Neoplasms / surgery