Epidemiology and Outcomes of Status Epilepticus

Int J Gen Med. 2021 Jun 28:14:2965-2973. doi: 10.2147/IJGM.S295855. eCollection 2021.

Abstract

Status epilepticus (SE) is a neurological and medical emergency, defined as a condition resulting either from the failure of the mechanisms responsible of seizure self-limitation or from the initiation of mechanisms which lead to atypically prolonged seizures. Further than death, SE can have long-term consequences, including neuronal injury, depending on the type, cause and duration of seizures with severe associated disabilities. In Europe, SE shows an incidence rate ranging about 9 to 40/100,000/y. In adults, mortality of patients with SE is ~30%, and even higher (up to 40%) in refractory status epilepticus. To date, etiology, duration, presence of comorbidity, level of consciousness, semiology and age are the main clinical predictors of SE outcome.

Keywords: classification; etiology; incidence; mortality; status epilepticus.

Publication types

  • Review