Management of amblyopia in pediatric patients: Current insights

Eye (Lond). 2022 Jan;36(1):44-56. doi: 10.1038/s41433-021-01669-w. Epub 2021 Jul 7.

Abstract

Amblyopia is a cause of significant ocular morbidity in pediatric population and may lead to visual impairment in future life. It is caused due to formed visual deprivation or abnormal binocular interactions. Several risk factors in pediatric age group may lead to this disease. Author groups have tried managing different types of amblyopia, like anisometropic amblyopia, strabismic amblyopia and combined mechanism amblyopia, with optical correction, occlusion therapy, penalization, binocular therapy and surgery. We review historical and current management strategies of different types of amblyopia affecting children and outcomes in terms of visual acuity, binocularity and ocular deviation, highlighting evidence from recent studies. Literature searches were performed through Pubmed. Risk factors for amblyopia need to be identified in pediatric population as early in life as possible and managed accordingly, as visual outcomes in amblyopia are best if treated at the earliest. Although, monocular therapies like occlusion or penalization have been shown to be quite beneficial over the years, newer concepts related to binocular vision therapy are still evolving.

摘要: 弱视是儿童重要的眼病之一, 并可能对今后的视力造成损害。它是由于形觉剥夺或不正常的双眼交互运动而引起的。儿童期的多种危险因素可导致本病的发生。本团队尝试了光学矫正、遮盖疗法、药物压抑疗法、双眼治疗和手术等方法, 以治疗不同类型的弱视, 如屈光参差性弱视、斜视性弱视以及斜视联合屈光参差性弱视。我们从视力、双眼协调能力和眼位偏差的结果, 回顾了影响儿童不同类型弱视的以往和当前的治疗策略, 并重点强调了近期的研究证据。我们对Pubmed进行了文献检索。儿童弱视的危险因素需要尽早察觉, 并进行相应的治疗和管理, 因为越早治疗, 弱视的视力恢复越好。尽管像遮盖疗法或药物压抑疗法这样的单眼治疗多年来被证明是非常有益的, 但与双眼治疗相关的新概念仍在不断更新。.

Publication types

  • Review

MeSH terms

  • Amblyopia* / therapy
  • Child
  • Humans
  • Sensory Deprivation
  • Strabismus* / complications
  • Strabismus* / therapy
  • Vision, Binocular
  • Vision, Low*
  • Visual Acuity