miR-133b targets NCAPH to promote β-catenin degradation and reduce cancer stem cell maintenance in non-small cell lung cancer

Signal Transduct Target Ther. 2021 Jul 7;6(1):252. doi: 10.1038/s41392-021-00555-x.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • A549 Cells
  • Carcinoma, Non-Small-Cell Lung / genetics
  • Carcinoma, Non-Small-Cell Lung / metabolism*
  • Cell Cycle Proteins / genetics
  • Cell Cycle Proteins / metabolism*
  • Humans
  • Lung Neoplasms / genetics
  • Lung Neoplasms / metabolism*
  • MicroRNAs / genetics
  • MicroRNAs / metabolism*
  • Neoplasm Proteins / genetics
  • Neoplasm Proteins / metabolism*
  • Neoplastic Stem Cells / metabolism*
  • Nuclear Proteins / genetics
  • Nuclear Proteins / metabolism*
  • Proteolysis*
  • RNA, Neoplasm / genetics
  • RNA, Neoplasm / metabolism*
  • beta Catenin / genetics
  • beta Catenin / metabolism*

Substances

  • CTNNB1 protein, human
  • Cell Cycle Proteins
  • MIRN133 microRNA, human
  • MicroRNAs
  • NCAPH protein, human
  • Neoplasm Proteins
  • Nuclear Proteins
  • RNA, Neoplasm
  • beta Catenin