Spontaneous bleeding from orbital haemangioma in drug-induced thrombocytopaenia

Chu Yu Yen; Chun-Chen Chen

doi:10.1136/bcr-2021-241741

Spontaneous bleeding from orbital haemangioma in drug-induced thrombocytopaenia

BMJ Case Rep. 2021 Jul 6;14(7):e241741. doi: 10.1136/bcr-2021-241741.

Authors

Chu Yu Yen¹, Chun-Chen Chen^{2

3}

Affiliations

¹ Department of Ophthalmology, Taipei City Hospital Renai Branch, Taipei, Taiwan.
² Department of Ophthalmology, Taipei City Hospital Renai Branch, Taipei, Taiwan DAC03@tpech.gov.tw.
³ Institute of Clinical Medicine, National Yang-Ming University, Taipei, Taiwan.

Abstract

An 81-year-old woman, a drug-induced thrombocytopaenia (DITP) patient, presented with a case of spontaneous bleeding from an orbital haemangioma manifesting as a sudden onset of ocular pain, proptosis and limited eye movement. Image studies revealed an extraconal, cystic lesion with haemorrhage. The ophthalmopathy was caused by the bleeding of the orbital haemangioma and it was resolved after embolisation of the feeding vessels. Spontaneous bleeding of orbital haemangioma is rare. This case emphasises that DITP may be the cause of spontaneous bleeding of orbital haemangioma by precipitating the inflammatory reactions within the tumour, which further cause the haemodynamic disturbances and ultimate spontaneous bleeding.

Keywords: contraindications and precautions; haematology (drugs and medicines); hemangioma.

Publication types

Case Reports

MeSH terms

Aged, 80 and over
Exophthalmos*
Female
Hemangioma* / complications
Hemorrhage / chemically induced
Humans
Pharmaceutical Preparations*
Thrombocytopenia* / chemically induced

Substances

Pharmaceutical Preparations