Thyrotoxicosis: a rare presentation of molar pregnancy

BMJ Case Rep. 2021 Jul 5;14(7):e242131. doi: 10.1136/bcr-2021-242131.

Abstract

A 49-year-old woman, G8P7, presented with 1 week of worsening vaginal bleeding and abdominal cramps in the setting of a recently discovered unplanned pregnancy. Vaginal ultrasound findings and a significantly elevated human chorionic gonadotropin (hCG) level were concerning for molar pregnancy. She developed signs of hyperthyroidism on the night of admission, for which the endocrinology team was consulted. Laboratory data were consistent with hyperthyroidism. The patient was believed to have thyrotoxicosis secondary to molar pregnancy with concern for impending thyroid storm. Her mental health disorder and bacteraemia made taking care of her further challenging. She was started on a beta-blocker, antithyroid agent and intravenous corticosteroids. She underwent an uncomplicated suction dilation and curettage (D&C), with resolution of her symptoms a few days after. At a follow-up appointment, the patient continued to be asymptomatic and was feeling well.

Keywords: pregnancy; thyroid disease; thyrotoxicosis.

Publication types

  • Case Reports

MeSH terms

  • Antithyroid Agents
  • Female
  • Humans
  • Hydatidiform Mole* / diagnosis
  • Hydatidiform Mole* / diagnostic imaging
  • Middle Aged
  • Pregnancy
  • Thyroid Crisis*
  • Thyrotoxicosis* / complications
  • Thyrotoxicosis* / diagnosis
  • Thyrotoxicosis* / drug therapy
  • Vacuum Curettage

Substances

  • Antithyroid Agents