Immunological profile of neonatal osteomyelitis cases

Ikumi Sako; Hiroyuki Iijima; Toshihiro Matsui; Kensuke Shoji; Takashi Ishikawa; Akira Ishiguro

doi:10.1002/ccr3.4161

Immunological profile of neonatal osteomyelitis cases

Clin Case Rep. 2021 May 4;9(6):e04161. doi: 10.1002/ccr3.4161. eCollection 2021 Jun.

Authors

Ikumi Sako^{1

2}, Hiroyuki Iijima¹, Toshihiro Matsui³, Kensuke Shoji³, Takashi Ishikawa⁴, Akira Ishiguro²

Affiliations

¹ Department of General Pediatrics and Interdisciplinary Medicine National Center for Child Health and Development Tokyo Japan.
² Center for Postgraduate Education and Training National Center for Child Health and Development Tokyo Japan.
³ Division of Infectious Diseases Department of Medical Subspecialties National Center for Child Health and Development Tokyo Japan.
⁴ Division of Immunology National Center for Child Health and Development Tokyo Japan.

Abstract

Osteomyelitis in childhood is often hematogenous and neonates are generally prone to bacteremia because of immature immunity. Neonatal osteomyelitis occurs even in the absence of apparent immunological or perinatal abnormalities.

Keywords: Staphylococcus aureus; immunology; necrotic bone; neonate; osteomyelitis.

Publication types

Case Reports