A case of KIT negative extra-gastrointestinal stromal tumor arising in the greater omentum with predominant cystic formation

Katsuya Nanjo; Yusuke Nishimuta; Mitsutoshi Miyasaka; Kenji Shinozaki; Daisuke Tsurumaru; Kousei Ishigami

doi:10.1016/j.radcr.2021.05.061

A case of KIT negative extra-gastrointestinal stromal tumor arising in the greater omentum with predominant cystic formation

Radiol Case Rep. 2021 Jun 20;16(8):2315-2318. doi: 10.1016/j.radcr.2021.05.061. eCollection 2021 Aug.

Authors

Katsuya Nanjo¹, Yusuke Nishimuta², Mitsutoshi Miyasaka², Kenji Shinozaki¹, Daisuke Tsurumaru³, Kousei Ishigami³

Affiliations

¹ Department of Radiology, National Hospital Organization Kyushu Cancer Center, 3-1-1 Notame, Minami-ku, Fukuoka, 811-1395, Japan.
² Department of Gastrointestinal Endoscopy, National Hospital Organization Kyushu Cancer Center, 3-1-1 Notame, Minami-ku, Fukuoka, 811-1395, Japan.
³ Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.

Abstract

We report a rare case of KIT-negative extra-gastrointestinal stromal tumor, in a 40-year-old woman. Contrast-enhanced computed tomography and magnetic resonance imaging revealed a >15-cm mass of multiple cystic lesions in the greater omentum. Histopathological findings after surgery showed a sheet-like growth of stellate tumor cells from epithelial cells, cystic degeneration, and mucus-like stroma. Immunohistochemistry was positive for discovered on GIST-1 (DOG1) but negative for CD117 (c-kit).

Keywords: Extra-gastrointestinal stromal tumor; Gastrointestinal stromal tumor; Greater omentum; KIT.

Publication types

Case Reports