Physical activity and self-reported sleep quality in adults with multiple sclerosis

Abstract

Background: There is a fourfold higher prevalence of sleep problems in multiple sclerosis (MS) than the general population.

Objective: This study examined cross-sectional associations among device-measured sedentary and physical activity behavior with perceived sleep quality in adults with MS.

Methods: Adults with MS (N = 290) completed the Pittsburgh Sleep Quality Index (PSQI) and wore an accelerometer for seven days providing a measure of time spent in sedentary behavior, light physical activity (LPA), and moderate-to-vigorous physical activity (MVPA) using MS-specific cut-points. We conducted multiple linear regression analysis to identify the independent contributions of variables for explaining PSQI scores.

Results: The overall model accounted for 2% of the variance in global PSQI scores, and MVPA was significantly and independently associated with global PSQI scores (β = ─0.123; p = 0.045; partial r = ─0.118) when accounting for average wear time, sedentary behavior, and time spent in LPA. There were no other significant associations with PSQI global score.

Conclusions: Our results suggest that time spent in MVPA may be associated with better sleep quality in adults with MS, but adults with MS do not spend sufficient time in physical activity. Researchers should evaluate these relationships in longitudinal study designs and behavior change interventions, as physical activity may provide a unique opportunity to improve sleep quality outcomes.

Keywords: Multiple sclerosis; Physical activity; Sedentary behavior; Sleep quality.