COVID-19 deep classification network based on convolution and deconvolution local enhancement

Comput Biol Med. 2021 Aug:135:104588. doi: 10.1016/j.compbiomed.2021.104588. Epub 2021 Jun 22.

Abstract

Computer Tomography (CT) detection can effectively overcome the problems of traditional detection of Corona Virus Disease 2019 (COVID-19), such as lagging detection results and wrong diagnosis results, which lead to the increase of disease infection rate and prevalence rate. The novel coronavirus pneumonia is a significant difference between the positive and negative patients with asymptomatic infections. To effectively improve the accuracy of doctors' manual judgment of positive and negative COVID-19, this paper proposes a deep classification network model of the novel coronavirus pneumonia based on convolution and deconvolution local enhancement. Through convolution and deconvolution operation, the contrast between the local lesion region and the abdominal cavity of COVID-19 is enhanced. Besides, the middle-level features that can effectively distinguish the image types are obtained. By transforming the novel coronavirus detection problem into the region of interest (ROI) feature classification problem, it can effectively determine whether the feature vector in each feature channel contains the image features of COVID-19. This paper uses an open-source COVID-CT dataset provided by Petuum researchers from the University of California, San Diego, which is collected from 143 novel coronavirus pneumonia patients and the corresponding features are preserved. The complete dataset (including original image and enhanced image) contains 1460 images. Among them, 1022 (70%) and 438 (30%) are used to train and test the performance of the proposed model, respectively. The proposed model verifies the classification precision in different convolution layers and learning rates. Besides, it is compared with most state-of-the-art models. It is found that the proposed algorithm has good classification performance. The corresponding sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and precision are 0.98, 0.96, 0.98, and 0.97, respectively.

Keywords: COVID-19 classification network; Convolution; Deconvolution; Enhanced CT features; ROI extraction.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Algorithms
  • COVID-19*
  • Datasets as Topic
  • Deep Learning*
  • Humans
  • SARS-CoV-2