Vertical transmission potential of SARS-CoV-2 from infected mother to twin neonates

Liangyu Peng; Suliman Khan; Ashaq Ali; Saeed Ahmed; Liaqat Ali; Guang Han; Yang Jing

doi:10.2217/fvl-2020-0324

Vertical transmission potential of SARS-CoV-2 from infected mother to twin neonates

Future Virol. 2021 May:10.2217/fvl-2020-0324. doi: 10.2217/fvl-2020-0324.

Authors

Liangyu Peng¹, Suliman Khan², Ashaq Ali^{3

4}, Saeed Ahmed⁵, Liaqat Ali⁵, Guang Han⁶, Yang Jing⁷

Affiliations

¹ Department of Gynecology & Obstetrics, Renmin Hospital of Wuhan University, Wuhan, 430010, China.
² The Second Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
³ State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, 430070, China.
⁴ University of Chinese Academy of Sciences, Beijing, 100049, China.
⁵ Department of Biological Sciences, National University of Medical Sciences, Rawalpindi, 46000, Pakistan.
⁶ Department of Radiation Oncology, Hubei Cancer Hospital, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, 430070, China.
⁷ Reproductive Medicine Center, Renmin Hospital of Wuhan University, Jiefang Road 238, Wuhan, 430060, China.

Abstract

Background: Limited details are available regarding the vertical transmission potential of COVID-19 infection in pregnant women. The authors' current study aimed to report the vertical transmission potential of COVID-19 infection in a woman pregnant with twins. Case description: The authors report the case of a 27-year-old woman infected with SARS-CoV-2. The patient was pregnant with dichorionic diamniotic fraternal twins and admitted to Renmin Hospital of Wuhan University, Wuhan, China. After undergoing a cesarean section, the patient gave birth to premature twins, who tested positive for COVID-19 infection. Interpretation: Findings from this case suggest a possibility of intrauterine infection caused by vertical transmission in a woman infected with COVID-19.

Keywords: COVID-19 infection; pregnancy outcomes; twins; vertical transmission.

Publication types

Case Reports