Human Gait Analysis in Neurodegenerative Diseases: A Review

IEEE J Biomed Health Inform. 2022 Jan;26(1):229-242. doi: 10.1109/JBHI.2021.3092875. Epub 2022 Jan 19.

Abstract

This paper reviews the recent literature on technologies and methodologies for quantitative human gait analysis in the context of neurodegenerative diseases. The use of technological instruments can be of great support in both clinical diagnosis and severity assessment of these pathologies. In this paper, sensors, features and processing methodologies have been reviewed in order to provide a highly consistent work that explores the issues related to gait analysis. First, the phases of the human gait cycle are briefly explained, along with some non-normal gait patterns (gait abnormalities) typical of some neurodegenerative diseases. Then the paper reports the most common processing techniques for both feature selection and extraction and for classification and clustering. Finally, a conclusive discussion on current open problems and future directions is outlined.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Algorithms
  • Gait
  • Gait Analysis*
  • Humans
  • Neurodegenerative Diseases* / diagnosis