Digestive Decolonization of Colorectal Carriage of Vancomycin-resistant Enterococcus faecium in a Japanese Adult

Intern Med. 2022 Jan 15;61(2):249-252. doi: 10.2169/internalmedicine.6088-20. Epub 2021 Jun 26.

Abstract

Patients with vancomycin-resistant Enterococcus (VRE) colonization should be managed in an isolation room with contact precautions. We herein report a patient whose colorectal carriage of VRE was successfully decolonized using concomitant bowel irrigation with polyethylene glycol, probiotics, and oral antimicrobials, linezolid and orally-administered daptomycin, for release from isolation and contact precautions. We therefore would like to suggest a potential strategy for managing patients with VRE colonization.

Keywords: decolonization; isolation precautions; vancomycin-resistant Enterococcus.

MeSH terms

  • Adult
  • Anti-Bacterial Agents / therapeutic use
  • Colorectal Neoplasms* / drug therapy
  • Enterococcus faecium*
  • Gram-Positive Bacterial Infections* / drug therapy
  • Humans
  • Japan
  • Vancomycin / therapeutic use

Substances

  • Anti-Bacterial Agents
  • Vancomycin