A Pancreas-Specific Ptf1a-Driven Cre Mouse Line Causes Paternally Transmitted Germline Recombination

Gastroenterology. 2021 Nov;161(5):1695-1697.e4. doi: 10.1053/j.gastro.2021.06.050. Epub 2021 Jun 24.

Authors

Derya Kabacaoğlu¹, Dietrich A Ruess², Kivanç Görgülü¹, Katja Steiger³, Marina Lesina¹, Hana Algül⁴

Affiliations

¹ Comprehensive Cancer Center Munich CCCM, Technische Universität München, Munich, Germany.
² Department of General and Visceral Surgery, Center of Surgery, Medical Center-University of Freiburg, Freiburg, Germany.
³ Comparative Experimental Pathology, Institute of Pathology, Technische Universität München, Munich, Germany.
⁴ Comprehensive Cancer Center Munich CCCM, Technische Universität München, Munich, Germany. Electronic address: hana.alguel@mri.tum.de.

PMID: 34175279
DOI: 10.1053/j.gastro.2021.06.050

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Animals
Female
Genotype
Humans
Integrases / genetics*
Integrases / metabolism
Male
Mice, Transgenic
Mutation
Paternal Inheritance*
Phenotype
Promoter Regions, Genetic
Proto-Oncogene Proteins c-rel / genetics
Proto-Oncogene Proteins c-rel / metabolism
Proto-Oncogene Proteins p21(ras) / genetics
Recombination, Genetic*
Transcription Factor RelB / genetics
Transcription Factor RelB / metabolism
Transcription Factors / genetics*

Substances

Proto-Oncogene Proteins c-rel
Relb protein, mouse
Transcription Factors
transcription factor PTF1
Transcription Factor RelB
Cre recombinase
Integrases
Hras protein, mouse
Proto-Oncogene Proteins p21(ras)