The HIF1α-PFKFB3 Pathway: A Key Player in Diabetic Retinopathy

J Clin Endocrinol Metab. 2021 Oct 21;106(11):e4778-e4780. doi: 10.1210/clinem/dgab469.

Authors

Teresa Vezza¹, Víctor M Víctor^{1

2

3}

Affiliations

¹ Service of Endocrinology and Nutrition, University Hospital Doctor Peset, Foundation for the Promotion of Health and Biomedical Research in the Valencian Region (FISABIO), 46017 Valencia, Spain.
² Department of Physiology, University of Valencia, 46010 Valencia, Spain.
³ CIBERehd-Department of Pharmacology University of Valencia, 46010 Valencia, Spain.

No abstract available

Keywords: HIF1α; PFKFB3; diabetic retinopathy; mitochondria; oxidative stress.

Publication types

Editorial
Research Support, Non-U.S. Gov't
Comment

MeSH terms

Diabetes Mellitus*
Diabetic Retinopathy*
Humans
Phosphofructokinase-2 / metabolism
Signal Transduction

Substances

PFKFB3 protein, human
Phosphofructokinase-2