"Titer of anti-HBs in health professions trainees: prevalence of antibody coverage in a University of Central Italy"

Hum Vaccin Immunother. 2022 Dec 31;18(1):1886805. doi: 10.1080/21645515.2021.1886805. Epub 2021 Jun 24.

Abstract

Objective: This observational retrospective study aims at verifying hepatitis-B-virus (HBV) vaccination coverage in students vaccinated before and after 1992, in order to optimize health surveillance and vaccination recall.

Methods: Vaccination status was evaluated using the anti-HBs antibody titer (anti-HBs). Student t-test and the chi-square test were performed to identify the average age and the difference in antibody coverage between the two genders and in the two populations analyzed.

Results: Our study outlined a prevalence of 21.83% uncovered trainees among those vaccinated at age 12 and 45.03% among those vaccinated in neonatal age.

Conclusion: In conclusion, our data showed persistent protection against HBV infection in healthcare students.

Keywords: Anti-HBs; Antibodies; assessment risk; health students; hepatitis B; vaccination; viral hepatitis vaccines.

Publication types

  • Observational Study

MeSH terms

  • Adolescent
  • Adult
  • Child
  • Female
  • Health Occupations
  • Hepatitis B Antibodies*
  • Hepatitis B Surface Antigens
  • Hepatitis B Vaccines
  • Hepatitis B virus*
  • Humans
  • Infant, Newborn
  • Italy / epidemiology
  • Male
  • Middle Aged
  • Prevalence
  • Retrospective Studies
  • Vaccination
  • Young Adult

Substances

  • Hepatitis B Antibodies
  • Hepatitis B Surface Antigens
  • Hepatitis B Vaccines