First description of hematogenously metastasized sclerosing epithelioid fibrosarcoma arising in the uterine cervix

Marie-Lisa Eich; Bernd Morgenstern; Michael Puesken; Roberto Pappesch; Alexander Quaas; Birgid Schoemig-Markiefka

doi:10.1016/j.gore.2021.100801

First description of hematogenously metastasized sclerosing epithelioid fibrosarcoma arising in the uterine cervix

Gynecol Oncol Rep. 2021 Jun 5:37:100801. doi: 10.1016/j.gore.2021.100801. eCollection 2021 Aug.

Authors

Marie-Lisa Eich¹, Bernd Morgenstern², Michael Puesken³, Roberto Pappesch¹, Alexander Quaas¹, Birgid Schoemig-Markiefka¹

Affiliations

¹ Institute for Pathology, University Hospital Cologne, Cologne, Germany.
² Department of Obstetrics and Gynecology, Medical Faculty, University Hospital Cologne, Cologne, Germany.
³ Institute of Diagnostic and Interventional Radiology, University Hospital of Cologne, Cologne, Germany.

Abstract

•First Case of hematogenously metastasized sclerosing epithelioid fibrosarcoma arising primarily in the cervix uteri.•Tumor cells were strongly and diffusely positive for MUC4.•Tumor showed a rare EWSR1-CREB3L2 gene fusion.

Keywords: Cervix; Epithelioid; Fibrosarcoma; SEF; Sclerosing; Uterine.

Publication types

Case Reports