Accuracy of Magnetic Resonance Imaging in Evaluating the Depth and Level of Invasion of Buccal Carcinoma: A Prospective Cohort Study

Yuxin Wang; Minghui Mao; Jinzhong Li; Zhien Feng; Lizheng Qin; Zhengxue Han

doi:10.1016/j.joms.2021.05.008

Accuracy of Magnetic Resonance Imaging in Evaluating the Depth and Level of Invasion of Buccal Carcinoma: A Prospective Cohort Study

J Oral Maxillofac Surg. 2022 Jan;80(1):185-196. doi: 10.1016/j.joms.2021.05.008. Epub 2021 May 18.

Authors

Yuxin Wang¹, Minghui Mao², Jinzhong Li², Zhien Feng³, Lizheng Qin⁴, Zhengxue Han⁵

Affiliations

¹ Resident, Department of Oral and Maxillofacial-Head and Neck Oncology, Beijing Stomatological Hospital, Capital Medical University, Beijing, China. Electronic address: wangyuxinxh@sina.cn.
² Attending Doctor, Department of Oral and Maxillofacial-Head and Neck Oncology, Beijing Stomatological Hospital, Capital Medical University, Beijing, China.
³ Associate Professor, Department of Oral and Maxillofacial-Head and Neck Oncology, Beijing Stomatological Hospital, Capital Medical University, Beijing, China.
⁴ Professor, Department of Oral and Maxillofacial-Head and Neck Oncology, Beijing Stomatological Hospital, Capital Medical University, Beijing, China.
⁵ Department Head, Department of Oral and Maxillofacial-Head and Neck Oncology, Beijing Stomatological Hospital, Capital Medical University, Beijing, China. Electronic address: hanf1989@hotmail.com.

PMID: 34157294
DOI: 10.1016/j.joms.2021.05.008

Abstract

Purpose: This study evaluated the accuracy of magnetic resonance imaging (MRI) in determining the depth and level of invasion of buccal carcinoma.

Methods: Patients with buccal squamous cell carcinoma diagnosed pathologically from July 2016 to December 2019 were included. The depth of invasion (DOI) and level of invasion (LOI) were evaluated by MRI, intraoperative specimens and pathological sections. Statistical analyses were performed using IBM SPSS software version 25.0 (IBM Corp., Armonk, NY).

Results: Forty-nine patients were ultimately included. The overall difference in DOI between MRI and pathological sections (DMP) was 5.55 ± 2.40 mm, and T category correlated with the differences in DOI measurement and LOI assessment. The threshold value of DOI by MRI to identify lymph node metastasis was 8.5 mm, and that for overall survival (OS) and disease-specific survival (DSS) was 14.1 mm for both. Buccinator invasion on MRI correlated with OS and DSS.

Conclusion: Tumors with MRI-derived DOI larger than 8.5 mm deserve simultaneous neck dissection at initial surgery. Buccinator invasion was found to be an independent prognostic factor for buccal carcinoma patients.

MeSH terms

Carcinoma, Squamous Cell* / diagnostic imaging
Carcinoma, Squamous Cell* / pathology
Carcinoma, Squamous Cell* / surgery
Humans
Magnetic Resonance Imaging
Neoplasm Invasiveness / pathology
Neoplasm Staging
Prognosis
Prospective Studies
Retrospective Studies
Tongue Neoplasms* / pathology