Diagnosis, prevention, and treatment of coronavirus disease: a review

Expert Rev Anti Infect Ther. 2022 Feb;20(2):243-266. doi: 10.1080/14787210.2021.1944103. Epub 2021 Jul 13.

Abstract

Introduction: Coronavirus disease (COVID-19) was first reported in Wuhan, China, in late December 2019 and subsequently, declared a pandemic. As of 3 June 2021, 172,493,290 individuals have acquired COVID-19 and 3,708,334 patients have died worldwide, according to the World Health Organization.

Areas covered: This review explores epidemiology; virology; pathogenesis; genomic variations; mode of transmission; clinical occurrence; diagnosis; and treatment with antiviral agents, antibiotics, and supportive therapies. It covers a nanotechnology-based treatment approach and emphasizes the importance of herbal and marine antiviral drugs. The review attempts to explain current advances in research, prevention, and control of COVID-19 spread through artificial intelligence and vaccine development status under cosmopolitan consideration.

Expert opinion: While COVID-19 research is advancing at full capacity, the discovery of drugs or vaccines that can fight the pandemic is necessary. Human survival in such a critical situation will be possible only with the development of strong immunity by opting for exercise, yoga, and consumption of hygienic food and beverages. Therefore, education about COVID-19 lethality and its impact on livelihood is important. The pandemic has also shown positive effects on the environment, such as a significant reduction in environmental pollution and global warming and improvement in river water quality.

Keywords: Antiviral therapy; Artificial intelligence; COVID-19; Nanotechnology; SARS-COV-2.

Publication types

  • Review

MeSH terms

  • Antiviral Agents / therapeutic use
  • Artificial Intelligence
  • COVID-19* / diagnosis
  • COVID-19* / prevention & control
  • COVID-19* / therapy
  • Humans
  • Pandemics
  • SARS-CoV-2

Substances

  • Antiviral Agents