Antimicrobial peptides: triumphs and challenges

Zi-Zhen Zeng; Shu-Hui Huang; Valérie Alezra; Yang Wan

doi:10.4155/fmc-2021-0134

Antimicrobial peptides: triumphs and challenges

Future Med Chem. 2021 Aug;13(16):1313-1315. doi: 10.4155/fmc-2021-0134. Epub 2021 Jun 21.

Authors

Zi-Zhen Zeng¹, Shu-Hui Huang², Valérie Alezra³, Yang Wan^{1

3}

Affiliations

¹ National Pharmaceutical Engineering Center for Solid Preparation in Chinese Herbal Medicine, Jiangxi University of Chinese Medicine, Nanchang, 330004, PR China.
² Jiangxi Maternal & Child Health Hospital, Nanchang, 330006, PR China.
³ Laboratoire de Méthodologie, Synthèse et Molécules Thérapeutiques (ICMMO), Université Paris-Sud, UMR 8182, CNRS, Université Paris-Saclay, Bât 410, Facultédes Sciences d'Orsay, Orsay, 291405, France.

PMID: 34148371
DOI: 10.4155/fmc-2021-0134

No abstract available

Keywords: PEGylation; antimicrobial peptides; clinical translation; hemolysis; peptidomimetic; prodrug; proteolytic instability; secondary structure; structure–activity relationship.

Publication types

Editorial
Research Support, Non-U.S. Gov't

MeSH terms

Anti-Bacterial Agents / chemistry
Anti-Bacterial Agents / pharmacology*
Antimicrobial Peptides / chemistry
Antimicrobial Peptides / pharmacology*
Bacteria / drug effects*
Drug Discovery
Drug Resistance, Bacterial / drug effects
Humans
Microbial Sensitivity Tests

Substances

Anti-Bacterial Agents
Antimicrobial Peptides