A Retrospective Cohort Study of Optimal Contrast for Successful Intussusception Reduction: Institutional Practices Matter

J Surg Res. 2021 Nov:267:159-166. doi: 10.1016/j.jss.2021.05.020. Epub 2021 Jun 17.

Abstract

Background: The first-line treatment for intussusception is radiologic reduction with either air-contrast enema (AE) or liquid-contrast enema (LE). The purpose of this study was to explore relationships between self-reported institutional AE or LE intussusception reduction preferences and rates of operative intervention and bowel resection.

Methods: Pediatric Health Information System (PHIS) hospitals were contacted to assess institutional enema practices for intussusception. A retrospective study using 2009-2018 PHIS data was conducted for patients aged 0-5 y to evaluate outcomes. Chi-squared tests were used to test for differences in the distribution of surgical patients by hospital management approach.

Results: Of the 45 hospitals, 20 (44%) exclusively used AE, 4 (9%) exclusively used LE, and 21 (46%) used a mixed practice. Of 24,688 patients identified from PHIS, 13,231 (54%) were at exclusive AE/LE hospitals and 11,457 (46%) were at mixed practice hospitals. Patients at AE/LE hospitals underwent operative procedures at lower rates than at mixed practice hospitals (14.8% versus 16.5%, P< 0.001) and were more likely to undergo bowel resection (31.1% versus 27.1%, P= 0.02).

Conclusions: Practice variation exists in hospital-level approaches to radiologic reduction of intussusception and mixed practices may impact outcomes.

Keywords: Pediatric radiology; Pediatric surgery; Quality improvement.

MeSH terms

  • Child
  • Child, Preschool
  • Enema / methods
  • Hospitals, Pediatric
  • Humans
  • Infant
  • Infant, Newborn
  • Institutional Practice
  • Intussusception* / diagnostic imaging
  • Intussusception* / surgery
  • Retrospective Studies
  • Treatment Outcome