Two cases of primary cutaneous candidiasis caused by Candida parapsilosis: a report and literature review

Abstract

Candida parapsilosis is a rare cause of primary cutaneous infection, with rare cases reported in the literature to date, most of the reports were immunocompromised individuals. Herein, we report two cases of primary cutaneous infection caused by C. parapsilosis in immunocompetent adults. C. parapsilosis were isolated and identified through morphological and molecular analyses, these isolates were found to be susceptible to itraconazole through in vitro antifungal susceptibility test. Both patients achieved clinical relief following oral itraconazole treatment. These two cases enriched the manifestations of cutaneous C. parapsilosis and highlight the importance of early diagnose and treatment.

Keywords: Antifungal susceptibility test; Candida parapsilosis; Immunocompetent; Molecular identification; Primary cutaneous candidiasis.