Objective: To review the advances in the computational fluid dynamics (CFD) in tissue engineering.
Methods: The latest research of CFD applied to tissue engineering were extensively retrieved and analyzed, the optimization of bioreactor design and the simulation of fluid dynamics and cell growth kinetics during tissue regeneration in vitro were mainly reviewed.
Results: The simulation and predictive capabilities of CFD can provide important guidance for the optimization of bioreactor design, and the cultivation of engineering tissue. The accuracy of model prediction results can be further improved by combining with experimental research.
Conclusion: As a new and effective research tool, CFD has its unique advantages in the application of tissue engineering. However, a more comprehensive and accurate simulation of the whole process of tissue regeneration still needs further studies.
目的: 综述计算流体力学（computational fluid dynamics，CFD）在组织工程中的应用进展。.
方法: 广泛查阅 CFD 应用于组织工程的相关文献，主要对 CFD 用于生物反应器设计改良或优化、模拟体外组织再生过程中的流体动力学和细胞生长动力学等方面进行综述。.
结果: CFD 的模拟预测能力可为生物反应器的设计优化和体外组织工程组织培养提供重要的指导作用，且结合实验研究能进一步提高模型预测结果的准确性。.
结论: CFD 作为新兴和有效的研究工具，已在组织工程中展现出独特优势并取得显著进展，但更全面、准确地模拟组织再生全过程仍需进一步研究。.
Keywords: Computational fluid dynamics; bioreactor; progress; tissue engineering; tissue regeneration.