Biosimilars accessible in the market for the treatment of cancer

J Control Release. 2021 Aug 10:336:112-129. doi: 10.1016/j.jconrel.2021.06.014. Epub 2021 Jun 11.

Abstract

Biosimilars are the biological product clinically identical to a biologic reference standard regarding their strength, purity, and safety. A large segment of biosimilars has been developed for the treatment of cancer. This review aims to discuss various facets of biosimilars and explicates on biosimilars accessible in the market for cancer clinical intervention. It also illustrates the outcomes of recent clinical trial studies concerning biosimilars. Further, it also crosstalk the safety profiles, regulatory approval requirements, and allied challenges therein. The work will be of significant interest to researchers working in the field of biologics and biosimilars.

Keywords: Biosimilars; biologics; cancers; clinical trials; marketed product; safety.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Biosimilar Pharmaceuticals*
  • Drug Approval
  • Humans
  • Neoplasms* / drug therapy

Substances

  • Biosimilar Pharmaceuticals